Senior Scientist in Mid-size Molecule Unit

Chugai Pharmabody Research Pte. Ltd. (“CPR”) was established in Singapore as a wholly-owned subsidiary of Chugai Pharmaceutical Co., Ltd(Chugai), a member of Roche group, in January 2012 and started operations on July 2, 2012. Located at Geneo in Singapore, it aims to generate new antibody drugs based on Chugai’s proprietary antibody engineering technologies, such as recycling antibody®, sweeping antibody®, bispecific antibody, various Fc engineered antibodies, and other new antibody engineering technologies that are under development. Pos ition – Senior Scientist in Mid-size Molecule UnitOverviewCPR is seeking a motivated Senior Scientist with demonstrated expertise in drug discovery, biotechnology and/or chemical biology, and a strong passion for medical science. This position offers the opportunity to contribute to the discovery and development of innovative drugs by applying and developing novel screening and peptide engineering technologies to address unmet medical needs.Reporting to the Research Manager, you will work closely with colleagues across research functions to advance drug discovery programmes. Following appropriate onboarding and familiarisation with laboratory instrumentation and experimental workflows, you will be expected to work independently.Key ResponsibilitiesLead peptide identification and screening activities, including: - Bead-based separation- ELISA- AlphaScreen- qPCR- NGS analysis- Robotic operationsDevelop novel screening technologies for drug discovery. Develop novel peptide engineering technologies.Propose and drive drug discovery projects from scientific concept through research activities.Collaborate with internal research teams to support the advancement of drug discovery programmes.Required QualificationsPhD in Biomedical Science, Biochemistry, Chemical Biology, Biotechnology, Information Science, or a related discipline with 0 – 3 years of relevant work experience.Fresh graduates are welcome to apply.Demonstrated technical expertise in one or more areas such as nucleic acid chemistry, biology or protein chemistry, supported by research projects, presentations and/or peer-reviewed scientific publications.Good command of spoken and written English. Strong organisational and communication skills, with the ability to work effectively in a team and manage multiple priorities.Preferred QualificationsDemonstrated strong expertise in at least one of the following areas:- Chemical biology or nucleic acid chemistry- Antibody, protein or peptide engineering- In vitro display or bio-panning techniques, such as phage display, cell display, DEL or SELEX - Research experience in oligonucleotide therapeutics, such as antisense oligonucleotides or siRNA- In vitro compartmentalisation, microfluidics or nanopore technology - Targeted protein degradation or RNA-targeting small molecule research- Lead identification and screening in drug discovery- Coding for wet-lab experiments, machine learning, big data analysis, data visualisation or business intelligence analysisA strong passion for medical science and innovative drug discovery, with a desire to contribute to developing innovative drugs for patients with unmet medical needs.Strong attention to detail and the ability to perform precise experimental work such as aseptic manipulation.Interested applicants are invited to email their detailed resume, as well as their qualifications, availability, current and expected salary to: [email protected] For more information regarding our Company, you may refer to our website at: http://chugai-pharmabody.com/We regret that only short-listed candidates will be notified